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DeCS
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Descriptor English:
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Genes, erbB-1
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Descriptor Spanish:
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Genes erbB-1
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Descriptor Portuguese:
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Genes erbB-1
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Synonyms English:
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c-erbB-1 Genes
erbB-1 Genes
v-erbB Genes
Genes, EGFR
Epidermal Growth Factor Receptor Genes
EGFR Genes
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Tree Number:
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G14.340.024.340.383.500.791.295.300
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Definition English:
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The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12. |
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Indexing Annotation English:
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spell in titles & translations as erbB-1; GENES, ERBB-2 is also available
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See Related English:
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Oncogene Proteins v-erbB
Receptor, Epidermal Growth Factor
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History Note English:
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95
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Allowable Qualifiers English:
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Record Number:
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32227
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Unique Identifier:
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D018773
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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